Big devices in small patients: Adapting adult ventricular assist devices for children

Complications in patients with ventricular assist devices.

Heart failure affects more than 5 million people in the United States. The treatments of this disease include medical therapy, heart transplantation, and the implantation of ventricular assist devices. These devices are used in patients who are no longer responsive to conservative medical treatment, who are not candidates for a heart transplantation (destination therapy), who are awaiting a hea...

Candidemia in patients with ventricular assist devices.

During the period 1998-2004, candidemia developed in 7 of 117 ventricular assist device recipients at our hospital, and the associated mortality rate was 71%. Five cases of candidemia were due to Candida parapsilosis, and 2 were due to Candida albicans. Three of the 7 patients with ventricular assist device-associated Candida bloodstream infections were cured, and the device was retained in 2 o...

Ventricular assist devices for all?

In the past 5 years, the numbers of ventricular assist device (VAD) systems implanted worldwide have increased exponentially. Thus, since the introduction of the HeartMate II LVAD by Thoratec (Thoratec Inc., Pleasanton, CA, USA) over 10 000 of these pumps have been implanted. The HVAD manufactured by HeartWare (HeartWare Inc., Framingham, MA, USA) has also found widespread application in Europe...

Left Ventricular Assist Devices.

Pediatric ventricular assist devices.

The field of pediatric mechanical circulatory support with ventricular assist devices has lagged significantly behind that of adult patients. However, there is increasing attention on the emerging field of pediatric ventricular assist device support. In this review, part of the Pediatric Cardiac Intensive Care Society/Extracorporeal Life Support Organization Joint Consensus Statement on Mechani...